李雪明 高级工程师
李雪明，男，汉族，广西桂林人，理学博士，高级工程师，硕士生导师。现在1946伟德国际源自英国工作。
一、教育与工作经历
2017年11月 – 至今，1946伟德国际源自英国，高级工程师。
2016年5月 - 2017年8月，广州优瓦科技有限公司，技术总监。
2012年10月 - 2016年4月，成都先导药物开发有限公司，助理总监。
2012年6月 - 2012年9月，桂林南药股份有限公司，高级研发员。
2011年7月 - 2012年5月，成都睿智化学研究有限公司，高级合成研究员。
2006年9月 – 2011年7月 中山大学药学院，有机化学专业，有机合成及不对称催化方向，硕博连读，获理学博士学位。
2002年9月 – 2006年7月 中山大学化学与化学工程学院，化学专业，获理学学士学位。
二、教学
主讲本科生《有机化学》《普通化学》《无机化学》《化工专业基础实验》《化学制药工艺学》等课程；研究生《结构化学》等课程。
三、科学研究
主要研究方向：
（1）有机合成化学的新反应、新方法
（2）有机光电材料的合成及其机理研究
（3）创新药物分子设计及合成
主要科研项目：
（1）广西科技厅, “带土移植”人才引 育计划, 新型光药理学治疗药物技术开发人才团队引进, 2024-05 至 2027-04, 100万元, 编号：桂科AA24010004, 主持；
（2）广西科技厅, 广西重点研发计划,创制化合物8-羟基喹啉锰锌原药合成技术研究及环保剂型开发应用, 2023-12 至 2026-11, 50万元, 编号：桂科AB23075166, 参与；
（3）广西科技厅，重点项目（粤桂联合基金项目），基于SIRTs家族调控的心肌能量代谢探讨血栓通防治心肌缺血的分子靶标和作用机制，编号：2022GXNSFDA080001，主持。
（4）广西科技厅，广西自然科学基金，二芳基苯并咪唑类有机电催化剂的构建及其在电化学合成中的应用，编号：桂科AD19110029，主持。
（5）伟德国际1946源于英国科研启动基金，新型有机电催化剂的构建及其电催化性能的研究，主持。
（6）国家自然科学基金委员会，地区科学基金项目，用于离液酶法保鲜的固定化酶及其酶促反应动力学研究，编号：32060521，参与。
（7）广西科技厅，重点项目，基于功能纳米材料的生物酶热稳定性的研究，编号：2020GXNSFDA297023，参与。
（8）广西科技厅，广西自然科学基金，海洋防腐涂料添加剂Cu2O@C的可控释放及防腐机理，编号：2018GXNSFAA294042，参与。
四、发表论文及专利
论文：
【2026年】
[37] He Zhao; Guangkuan Zhu; Yvhua Wang; Lin Mo; Tengchuan Jiang; Yunfei Liang; Shusheng Lai(*); Xueming Li(*), Tunable ultralong room-temperature phosphorescence from minoxidil-derived carbon-dot composites for multi-level information encryption, New Journal of Chemistry, 2026, 50(10): 4497-4503.
[36] Wen, Shenggui; Wang, Zaiwu(*); Weng, Jinghe; Li, Xueming(*), Integrated design of C2-Pyridyl-functionalized Polyaryl imidazole: Solvent/ light/acid/mechanical force quadruple-responsive properties construction for intelligent anti-counterfeiting, Journal of Photochemistry and Photobiology A: Chemistry , 2026, 475(-): 117031.
[35] Zhu, Guangkuan; Liang, Fengxian; Zhao, He; Han, Shu; Feng, Qiping; Liu, Yuehui; Zhang, Mengmeng*; Li, Xueming(*), Imidazole-based organic room-temperature phosphorescent materials with efficient emission at trace doping for information encryption, Journal of Luminescence, 2026, 291(-): 121705.
[34] Liang, Fengxian; Zhu, Guangkuan; Wang, Qingquan; Weng, Jinghe; Liao, Caizhen; Li, Xueming(*), Guest cyclization and melt processing synergistically enhance lifetime of organic room-temperature phosphorescence in DMAP-based host-guest systems, Dyes and Pigments, 2026, 246(-): 113366.
【2025年】
[33] Li, Ling; Xiong, Wenzhao; Zhang, Yanyan; Wang, Zhibo; Dong, Junyin; Zhu, Shenbo; Li, Xueming; Hu, Mengxing; Wu, Jiaying(*); Hu, Huawei(*); Hai, Jiefeng(*), Unsaturated Vinyl Branching: A Molecular-Tailoring Strategy for Synergistic Stacking Regulation and Energy-Loss Suppression Toward 20%-Efficiency Organic Solar Cells, Advanced Materials, 2025, 38(10): e20692.
[32] Li, Yuyi; Han, Shu; Zhao, He; Weng, Jinghe; Liu, Yuehui(*); Li, Xueming(*); Wang, Guixia, Efficient energy phosphorescence transfer and reversible phosphorescence in aromatic heterocyclic doped systems for advanced information storage, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2025, 336: 126053.
[31] Luo, Yang; Li, Xiaofen; Zou, Yueyun; Wu, Yu; Li, Yan(*); Wang, Kai; Li, Xueming, Fluorinated (3-diketonate lanthanide emitters containing pyrazine: Syntheses, crystal structures, Hirshfeld surface analyses, and luminescence properties, Inorganica Chimica Acta, 2025, 588: 122872.
[30] Weng, Jinghe; Wen, Shenggui; Liang, Fengxian; Li, Yuyi; Cui, Xinran; Li, Xueming(*), Halogen-enhanced highly efficient organic room temperature phosphorescent materials: Design, theoretical insights and applications, Dyes and Pigments, 2025, 242: 112939.
[29] Liu, Yuehui; Wang, Zaiwu; Chen, Chunyu; Liu, Yadan; Yu, Penglong; Guan, Peng(*); Li, Xueming(*), A Dual-Responsive Fluorescent Compound Exhibiting Turn-On Mechanoresponsive and Solvatochromism for Rewritable Optical Data Storage, ACS Omega, 2025, 10(40): 47300-47307.
[28] Li, Ling; Li, Na; Hai, Jiefeng(*); Gao, Shenzheng; Xu, Hao; Luo, Ming; Zhou, Xinjie; Shi, Xiaoyu; Xu, Shanlei; Li, Xueming; Lu, Zhenhuan; Pang, Youyong; Li, Ming; Xia, Haiping; Chen, Shangshang; Song, Xin, The impeded film-formation kinetics with ameliorated carrier trap density to construct efficient as-cast organic solar cells through short multi-branched alkylthio chains strategy, Chemical Engineering Journal, 2025, 503: 158263.
【2024年】
[27] Zha, Keyu; Li, Ling; Zhang, Jiyun; Tang, Sirou; Li, Xueming; Hai, Jiefeng; Fan, Dayong; Li, Ming; Liu, Yongping; Lu, Zhenhuan(*), Investigation the influence of bay substitution with perylene diimide on the photocatalytic performance of perylene-diimide/TiO2 composites, Journal of Photochemistry and Photobiology A: Chemistry , 2024, 451: 115517.
[26] Han, Shu; Li, Yuyi; Wang, Zaiwu; Li, Xueming(*); Wang, Guixia, Naphthyl substituted guest induce efficient room temperature phosphorescence by a triplet-triplet energy transfer mechanism, Dyes and Pigments, 2024, 228: 112243.
[25] Luo, Jiabin; Yu, Mengdan; Chu, Fangxu; Xiao, Zhiyin(*); Zhong, Wei; Li, Xueming; Liu, Xiaoming(*), The reaction of nonacarbonyldiiron with 8-alkynyloxyquinolines: Alkynyl activation, cyclization via C-N bond formation, and C-H bond cleavage, Applied Organometallic Chemistry, 2024, 38(6), c7488.
[24] Shi, Lijuan; Li, Xueming; Wang, Yongtao(*); Ma, Lei, Single component long-lived dynamic room temperature phosphorescence with large-scale preparation and visible light excitation, Journal of Molecular Structure, 2024, 1311: 138434.
【2023年】
[23] Jiang Jianfeng; Wang Yongtao(*); Ma Lei; Li Xueming(*); Wang Xiaojuan(*); Guo Yanjun, AIE activity, mechanochromic property and solvent inclusion of two β-diketones with tetraphenylethylene unit, Tetrahedron, 2023, 136: 133355.
[22] Wang, Zaiwu; Li, Zuyao; Huang, Junhao; Han, Shu; Li, Xueming(*); Wang, Zizhou(*), A Selective and Reversible Fluorescent Probe for Cu2+ and GSH Detection in Aqueous Environments, ChemistrySelect, 2023, 8(12): e202300012.
[21] Lei, Lele; Zhang, Jiyun; Zha, Keyu; Tang, Sirou; Hai, Jiefeng; Fan, Dayong; Li, Xueming; Li, Ming; Liu, Yongping; Lu, Zhenhuan(*), Hierarchical Self-Assembly of Organic-Inorganic Hybrid Nanosheets to Construct Tubular Superstructures for Photocatalytic Degradation, ACS Applied Nano Materials, 2023, 6(7): 6270-6278.
[20] Hai, Jiefeng(*); Li, Ling; Liu, Xin; Shi, Xiaoyu; Wang, Zhibo; Chen, Xuelan; Lu, Zhenhuan; Li, Xueming; Pang, Youyong; Yu, Jiangsheng*; Hu, Huawei*; Chen, Shangshang(*), Ending group modulation of asymmetric non-fullerene acceptors enables efficient green solvent processed organic solar cells, Chemical Engineering Journal, 2023, 462: 142178.
[19] Zhong, Wei(*); Luo, Jiabin; Liu, Zhenzhen; Zhan, Guangli; Zhu, Lihua; Lu, Chunxin; Shen, Zhongquan; Li, Xueming; Liu, Xiaoming(*), The mechanistic diversity of the selective aerobic oxidation of alcohols catalyzed by systems derived from CuI and a diamine ligand, Inorganic Chemistry Frontiers, 2023, 10(10): 3139-3150.
[18] Yanjin He, Yongtao Wang(*), Xueming Li, Yanjun Guo, Lei Ma, Breaking the bottleneck of organic light conversion agents: Preparation, performance evaluation and intrinsic mechanism, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 288: 122161.
【2022年】
[17] Gao, Ran; Wu, Qinggang; Zhang, Jiyun; Cen, Huan; Hai, Jiefeng; Li, Xueming; Zhang, Jinxiao; Lu, Zhenhuan(*), Organic N-type Dopants with a Phenyl Tertiary Carbon Structure: Molecular Structure and Doping Properties, ChemistrySelect, 2022, 7(48): e202204021.
[16 Luo Jia-Bin; Guo Jin-Zhong; Xiao Zhi-Yin(*); Zhong Wei; Li Xue-Ming(*); Liu Xiao-Ming, Preparation of Dicarbonyl Iron Compounds with a Bidentate Phosphine and Their CO Release Behaviors upon Irradiation, Chinese Journal of Inorganic Chemistry, 2022, 38(7): 1241-1251.
[15] Jiabin Luo, Chuanguo Cui, Zhiyin Xiao(*), Wei Zhong, Chunxin Lu, Xiujuan Jiang, Xueming Li(*), Xiaoming Liu, Iron(0) tricarbonyl η4-1-azadiene complexes and their catalytic performance in the hydroboration of ketones, aldehydes and aldimines via a non-iron hydride pathway, Dalton Trans., 2022, 51, 11558-11566
[14] Yongtao Wang(*), Zhean Qian, Xueming Li, Anjun Qin, Yanjun Guo, Benzhong Tang, Polymorphism and light conversion properties of anthracene-based isomers, Dyes and Pigments, 2022, 197, 109888
【2021年】
[13] Yongtao Wang(*), Zhean Qian, Xueming Li, Anjun Qin, Yanjun Guo and Benzhong Tang, Exploration of high-performance light-conversion agents based on cyanostilbene and phenanthrenecarbonitrile backbones: E/Z and position isomerism, high-contrast Michael addition reaction activity and intramolecular photocyclization, J. Mater. Chem. C, 2021,9, 12681-12693.
[12] Li-Ling Cai, Sheng-Mei Zhang, Yan Li(*), Kai Wang, Xue-Ming Li, Gilles Muller(*), Fu-Pei Liang, Ya-Tao Hu, Gui-Xia Wang, Lanthanide nitrato complexes bridged by the bis-tridentate ligand 2,3,5,6-tetra(2-pyridyl)pyrazine: Syntheses, crystal structures, Hirshfeld surface analyses, luminescence properties, DFT calculations, and magnetic behavior, Journal of Luminescence 2021, 232, 117835.
【2020年】
[11] Xie, Ya; Li, Xueming; Yan, Liqiang(*); Li, Jianping(*), A highly selective aggregation-induced emission fluorogen for sensitive detection of Al3+ in living cells, Luminescence, 2020, 35(1): 156-162.
[10] Wenjing Liu, Yongtao Wang(*), Jinfeng Yang, Xueming Li(*), Xiaojuan Wang(*), Lei Ma, The abnormal solvatochromism, high-contrast mechanochromism and internal mechanism of two AIEE-active β-diketones, Dyes and Pigments 2020, 175, 108149.
【2019年】
[9] Ya Xie, Xueming Li, Liqiang Yan(*) and Jianping Li(*), A highly selective aggregation‐induced emission fluorogen for sensitive detection of Al3+ in living cells, Luminescence, 35, 1, (156-162), (2019).
[8] Li Ling Cai, Ya Tao Hu, Yan Li(*), Kai Wang, Xiu Qing Zhang, Gilles Muller(*), Xue Ming Li, Gui Xia Wang, Solid-state luminescence properties, Hirshfeld surface analysis and DFT calculations of mononuclear lanthanide complexes (Ln = EuIII, GdIII, TbIII, DyIII) containing 4′-phenyl-2,2′:6′,2″-terpyridine, Inorganica Chimica Acta, 2019, 489, 85-92.
【2018年】
[7] Liqiang Yan, Xueming Li, Jianping Li(*), A Novel Turn-on Fluorescent Probe Based on Coumarin Schiff's base for Multichannel Monitoring of Al3+, Hg2+ and ClO in Different Solutions and its Applications. ChemistrySelect 2018, 3 (36), 10157-10163.
【2017年之前】
[6] Xue-ming Li, Bo Wang, Jun-min Zhang, and Ming Yan(*), Asymmetric Organocatalytic Double-Conjugate Addition of Malononitrile to Dienones: Efficient Synthesis of Optically Active Cyclohexanones, Org. Lett. 2011, 13 (3), 374-377.
[5] Nie, Shao-zhen; Hu, Zhi-peng; Xuan, Yi-ning; Wang, Jin-jia; Li, Xue-ming; Yan, Ming(*), Organocatalytic asymmetric conjugate addition of malonates to 3-nitro-2H-chromenes, Tetrahedron-Asymmetry, 2010, 21(16): 2055-2059.
[4] Xue-jing Zhang, Sheng-ping Liu, Xue-ming Li, Ming Yan(*) and Albert S. C. Chan, Highly enantioselective conjugate addition of aldehydes to nitroolefins catalyzed by chiral bifunctional sulfamides, Chem. Commun. 2009, (7), 833-835.
[3] Lao, Jin-hua; Zhang, Xue-jing; Wang, Jin-jia; Li, Xue-ming; Yan, Ming(*); Luo, Hai-bin, The effect of hydrogen bond donors in asymmetric organocatalytic conjugate additions, Tetrahedron-Asymmetry, 2009, 20(24): 2818-2822.
[2] 杨锦耀; 李雪明; 董立亭; 宣宜宁; 鄢明(*); 姚英明, 双功能有机小分子模拟酯酶研究, 有机化学, 2009, (04): 569-574.
[1] He, Shan Zhen; Li, Xue Ming; Dai, Jia; Yan, Ming(*), Synthesis of antidepressant duloxetine via asymmetric transfer hydrogenation, Chinese Chemical Letters, 2008, 19(1): 23-25.
专利：
[3] 李雪明; 王在武; 黄俊皓; 韩姝, 一种基于二苯甲酮和咪唑结构具有关-开可切换力致色变材料及其应用, 专利号：CN 115636793 B
[2] 李进, 李雪明, 窦登峰, 万金桥, 高剑，吡咯酰胺类化合物及其制备方法与用途，专利号：CN 105732458 B.
[1] 李进, 李雪明, 窦登峰, 万金桥, 高剑，一种制备吡咯酰胺类化合物的中间体化合物及其制备方法与应用，专利号：CN 105732597 B.
五、联系方式
通信地址：广西桂林市建干路12号，1946伟德国际源自英国（541004）
Email: lixueming@glut.edu.cn
